Meeting Banner
Abstract #5277

Is Iron Concentration Linked to Structural Connectivity in the Subthalamic Nucleus? Implications for Planning of Deep Brain Stimulation

Wahaj Patel1,2, Alexey Dimov3, Yi Wang3, Yihang Yao3, Brian Kopell4,5, and Rafael O’Halloran1,4

1Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States, 2The City College of New York, New York, NY, United States, 3Weill Cornell Medical College, 4Psychiatry, Icahn School of Medicine at Mount Sinai, 5Neurosurgery, Icahn School of Medicine at Mount Sinai

The relationship between iron concentration, evaluated via quantitative susceptibility mapping (QSM) and white matter connectivity, assessed with 3T MRI, was explored. Such a relationship might be useful in deep brain stimulation (DBS) surgical planning, where both QSM and white matter connectivity are gaining interest. For several relevant regions of interest in movement disorders such as the superior frontal, pre central and post central gyrus there was a strong correlation between STN connectivity and QSM intensity. To allow quick assessment of the spatial variation of connectivity in the STN, an RGB image was computed from connectivity in 3 regions of interest.

This abstract and the presentation materials are available to members only; a login is required.

Join Here