Purpose Our research aims to research abstinence and methadone maintenance treatment, to reveal which abstinence way is better and to compare their cue-reactivity in heroin-dependent individuals.
Materials and Methods 24 heroin-dependent patients under abstinence,19 heroin-dependent patients under MMT and 20 healthy volunteers were recruited. The functional images were acquired by using a spin-echo EPI.
Results MMT group brain regions which had differences in cue-reactivity intensity were significantly positive correlation with craving changes, and abstinence group did not exist. Discussion and Conclusion This study showed that abstinence is more advantageous than MMT to reduce heroin addiction in drug cue-reactivity.