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Abstract #5481

Factors influencing Data Quality in a Multi-Center Breast MR Spectroscopy Trial (ACRIN 6657 Extension)

Patrick J Bolan1, Benjamin A Herman2, Gregory J Metzger1, Eunhee Kim3, David C Newitt4, Savannah Partridge5, Michael Garwood1, Mark A Rosen6, and Nola M Hylton4

1Radiology, University of Minnesota, Minneapolis, MN, United States, 2Center for Statistical Sciences, Brown University, Providence, RI, United States, 3National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, United States, 4Radiology, University of California, San Francisco, CA, United States, 5Radiology, University of Washington, Seattle, WA, United States, 6Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA, United States

The ACRIN 6657-extension trial, the first multi-center trial using magnetic resonance spectroscopy (MRS) in breast cancer, has completed and its initial results have been recently published. This study reports on the quality of the MRS data and identifies technical and logistic factors that contributed to a lower-than-anticipated data yield.

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