The goal of this study was to compare the apparent transverse relaxation time (T2) constants of metabolites obtained using LASER and PRESS sequences in the human brain at 3 T. A 25% higher apparent T2s of total N-acetyl aspartate, total creatine and total choline were measured with LASER sequence as compared to PRESS while comparable apparent T2s were measured for strongly coupled metabolites, e.g., glutamate and myo-inositol, with both sequences.
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