This pilot study reports clear deregulation in the neurochemistry of defense personnel exposed to repeated blast. The changes recorded are different to those reported for mTBI, PTSD and chronic pain. No differences between blast exposed and healthy were recorded by MRI sequences T1WI, FLAIR or SWI. In vivo neuro 2D spectroscopy recorded deregulation with PC and GPC, NAA and GABA all decreased compared to the healthy non exposed brain. We we did not observe any changes in the fucosolated glycans, which are reflective of pain, repetitive brain injury and/or cognitive deficit.