Meeting Banner
Abstract #0048

Visually evoked negative BOLD signal coupled with silenced neuronal activity; an fMRI and intra-cranial electrocorticography study in humans

Alessio Fracasso1, Anna Gaglianese2, Serge O Dumoulin1, Nick F Ramsey2, and Natalia Petridou2

1Spinoza Centre for Neuroimaging, Amsterdam, Netherlands, 2University Medical Centre Utrecht, Utrecht, Netherlands

Neuroimaging techniques provide a unique window on the study of human brain function in healthy as well as pathological conditions. Intra-cranial electrocorticography (ECoG) at high frequency broadband power is associated with positive blood-oxygenation-level-dependent signal, but the electrophysiological correlates of negative BOLD signals are are less well understood. Here we investigate the relationship between negative BOLD and neuronal population activity measured with ECoG, in humans, using a paradigm that excludes blood stealing as a source of negative BOLD signal.

This abstract and the presentation materials are available to members only; a login is required.

Join Here