Meeting Banner
Abstract #0130

Whole-Body MRI for Metastatic Cancer Detection using T2-Weighted Imaging with Fat and Fluid Suppression

Xinzeng Wang1, Ali Pirasteh1, James Brugarolas2,3, Neil M. Rofsky1,4, Robert E. Lenkinski1,4, Ivan Pedrosa1,3,4, and Ananth J. Madhuranthakam1,4

1Radiology, UT Southwestern Medical Center, Dallas, TX, United States, 2Internal Medicine, UT Southwestern Medical Center, Dallas, TX, United States, 3Kidney Cancer Program, Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX, United States, 4Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States

Whole-body diffusion with background suppression (DWIBS) has increased sensitivity and specificity for metastatic cancer detection. However, DWIBS using echo-planar readout suffers from geometric distortions due to large B0 inhomogeneities associated with large FOV, used in whole-body MRI. Additionally, DWIBS suffers from low spatial resolution and long scan times due to low signal to noise ratio. In this work, we developed an alternative WB-MRI technique at 3T using fast, high-resolution and high-SNR T2-weighted imaging with simultaneous fat and fluid suppression, called DETECT. Patient studies show that, DETECT is time-efficient, robust, and generates distortion-free images with good lesion conspicuity, compared to DWIBS.

This abstract and the presentation materials are available to members only; a login is required.

Join Here