Meeting Banner
Abstract #0184

Quantification of flow hemodynamics using non-contrast enhanced 4-dimensional dynamic magnetic resonance angiography

Xingfeng Shao1, Danny J.J. Wang1, and Lirong Yan1

1Laboratory of FMRI Technology (LOFT), Mark & Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States

Arterial spin labeling (ASL)-based non-contrast enhanced dynamic MR angiography (NCE-dMRA) can provide not only dynamic flow depiction but also quantitative hemodynamics. According to the indicator dilution theory, we proposed a novel analytical solution for arterial blood flow (aBF) quantification in NCE-dMRA. Compared to the previous truncated singular value decomposition (t-SVD), reliable aBF measures were obtained using the proposed method from both simulation and experimental data. Hemodynamic maps including aBF, arterial blood volume and arterial transit time were successfully generated. Our preliminary patient data suggest that the dynamic flow patterns in conjunction with quantitative hemodynamic may provide complementary information for clinical diagnosis.

This abstract and the presentation materials are available to members only; a login is required.

Join Here