Abstract #0215

DP-TSE MRF: Rapid and Accurate T2 and ADC Quantification Using Diffusion-Prepared Turbo Spin-echo Magnetic Resonance Fingerprinting

Zhixing Wang^1,2, Xiaozhi Cao², Congyu Liao², Huihui Ye^2,3, Hongjian He², and Jianhui Zhong²

¹Biomedical Engineering, University of Virginia, Charlottesville, VA, United States, ²Center for Brain Imaging Science and Technology, Department of Biomedical Engineering, Zhejiang University, Hangzhou, China, ³State Key Laboratory of Modern Optical Instrumentation, College of Optical Science and Engineering, Zhejiang University, Hangzhou, China

This study proposes a rapid and accurate MR fingerprinting (MRF) framework based on a diffusion-prepared, turbo spin-echo (DP-TSE) sequence. Compared to both conventional parametric mapping and recent FISP-based MRF methods, the proposed framework provides accurate T₂ maps and three main apparent diffusion coefficients (ADCs) for 15 slices within 7 minutes. This new MRF strategy can achieve accurate, inherently co-registered, high resolution T2 and ADC maps simultaneously.

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