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Abstract #0270

Silent T1-Mapping Using the Variable Flip Angle Method with Zero Echo Time

Emil Ljungberg1,2, Ana Beatriz Solana Sanchez2, Tobias C Wood1, Shannon Kolind3,4,5, Florian Wiesinger2, and Gareth J Barker1

1Neuroimaging, King's College London, London, United Kingdom, 2GE Healthcare, Munich, Germany, 3Medicine, University of British Columbia, Vancouver, BC, Canada, 4Physics and Astronomy, University of British Columbia, Vancouver, BC, Canada, 5Radiology, University of British Columbia, Vancouver, BC, Canada

In this work we present a silent whole brain T1-mapping technique with zero echo time using a variable flip angle (VFA) scheme with a 3D radial sequence (RUFIS). The technique is compared to a conventional Cartesian gradient-echo based sequence (DESPOT1-HIFI) in a quantitative T1 phantom as well as in vivo in a single subject. Phantom measurements showed good agreement between techniques with average difference of 28 ms. In vivo T1 maps showed good correspondence between RUFIS and DESPOT1-HIFI.

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