Multi-spectral MRI reduces susceptibility when imaging near total joint arthroplasty (TJA). MAVRIC SL acquires 24 bins of off-resonance data to generate images, but most implants require fewer bins. This study uses a calibration scan, to determine an adequate number of bins, coupled with long echo trains and variable flip angles to permit an isotropic MAVRIC SL acquisition in clinically feasible scan times. The isotropic MAVRIC SL acquisition showed an improved detection of the implant-bone interface surrounding TJA, while retaining image contrast and overall SNR. An isotropic acquisition may improve the diagnostic capability of MAVRIC SL images.