Previous studies have demonstrated improved spatial specificity of conventional BOLD fMRI when restricting the analysis to the initial dip, however recent evidence suggests that it may be possible to achieve high specificity by restricting the analysis to the early phase of the response. Here we tested this concept by employing a spatial resolution test pattern in the visual cortex and observed the evolution of this pattern over time in signal subjects. We find that the spatial pattern of the early stages of the BOLD response appear to exhibit improved spatial specificity.
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