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Abstract #0443

Structural Determination Using 129Xe NMR Line-shape in Chemical Shift Imaging

Stephen Kadlecek1, Mehrdad Pourfathi1, Luis Loza1, Ian Duncan1, Kai Ruppert1, Hooman Hamedani1, Sarmad Siddiqui1, Yi Xin1, Faraz Amzajerdian1, Harrilla Profka1, Ryan Baron1, Mary Spencer1, Tahmina Achekzai1, Shampa Chatterjee2, Maurizio Cereda3, and Rahim R. Rizi1

1Radiology, University of Pennsylvania, Philadelphia, PA, United States, 2Physiology, University of Pennsylvania, Philadelphia, PA, United States, 3Anesthesiology and Critical Care, University of Pennsylvania, Philadelphia, PA, United States

We present a method to discriminate dissolved 129Xe spectra by tissue type and location based on local variations in T2*. Mixed contributions of parenchyma and vasculature can be separated almost completely. The method is particularly useful to high field imaging in species lacking distinct dissolved phase spectral components.

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