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Abstract #0528

Profiling myelin maturation with quantitative susceptibility mapping (QSM) in pediatric brains

Lijia Zhang1 and Allen Song1

1Brain Imaging and Analysis Center, Duke University, Durham, NC, United States

Quantitative susceptibility mapping (QSM) has been increasingly used to access brain development, especially white matter myelination. In this study, diffusion tensor imaging (DTI) has been used to delineate the corpus callosum in the pediatric brains, followed by tract-based QSM analysis to accurately derive the baseline susceptibility across subjects. The baseline susceptibility is then used to evaluate white matter and myelin development.

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