Water-fat separation can improve the quality of tissue parameter maps in quantitative imaging methods such as Magnetic Resonance Fingerprinting (MRF). We propose such a technique that uses the B0 map as prior information for spiral off-resonance correction through conjugate phase reconstruction, enabling efficient water-fat separation with only two echo points per frame, implemented in a single run MRF approach. With this technique, accurate tissue parameter maps can be produced in the presence of fat.
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