Abstract #0741

Validation of Diffusion Spectrum Imaging of the Human Tongue with Histology

Nahla M H Elsaid¹, Adam C Puche², Maureen Stone³, Jerry L Prince⁴, Steven Roys¹, Rao P Gullapalli¹, and Jiachen Zhuo¹

¹Diagnostic Radiology, University of Maryland School of Medicine, Baltimore, MD, United States, ²Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, MD, United States, ³Neural and Pain Sciences and Orthodontics, University of Maryland School of Dentistry, Baltimore, MD, United States, ⁴Electrical and Computer Engineering, Johns Hopkins University, Baltimore, MD, United States

In this study provides validation procedure for DSI anisotropy measures versus the histological analysis of the aligned tongue muscles. A fresh ex-vivo sample of the tongue is scanned using DSI multi-shell acquisition then the sample is fixed for further histological analysis and comparison with the fiber tracts using DSI reconstruction. The DSI delineation of muscle fibers is matching the histology images of the same region.

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