Abstract #0770

Investigating the use of non-contrast enhanced Magnetic Resonance Multi-Sequence Thrombus Imaging (MSTI) to direct therapy in patients with acute iliofemoral Deep Vein Thrombosis

Justinas Silickas¹, Prakash Saha¹, Alberto Smith¹, Stephen Black², Adam Gwozdz¹, Marcelo Andia Kohnenkampf³, Ashish Patel¹, Bijan Modarai¹, Rene Botnar⁴, and Alkystis Phinikaridou⁴

¹Academic Department of Vascular Surgery, King's College London, London, United Kingdom, ²Vascular Surgery Department, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom, ³School of Medicine, Pontificia Universidad Católica de Chile, Santiago, Chile, ⁴School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom

Deep vein thrombosis (DVT) affects 1 in 1000 people and when the ilio-femoral segment is involved, over half will develop post-thrombotic syndrome (PTS). PTS can be debilitating for the patients and carries a huge health cost burden. Thrombolysis reduces the incidence of PTS, but is only successful in 60% of patients. There is no reliable method of identifying thrombi susceptible to lysis. We have developed a non-contrast-enhanced magnetic resonance multi-sequence thrombus imaging (MSTI) protocol that provides information on the structural composition of the thrombus and may be a reliable method of predicting thrombus lysability.

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