Though conventional and advanced MR imaging studies such as perfusion and MR spectroscopy are useful for evaluating brain tumors, there remains a need for a rapid, quantitative, and non-invasive method. Magnetic Resonance Fingerprinting (MRF) utilizes pseudo-randomized acquisition parameters to simultaneously quantify multiple tissue properties including T1 and T2 relaxation times. A previous 2D MRF study quantitatively differentiated between solid tumor and peri-tumoral white matter regions of various brain tumors. In this ongoing study we demonstrate the capability of volumetric 3D MRF to improve lesion characterization between adult intra-axial brain neoplasms using first- and second- order radiomic analysis.
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