Readout-segmented echo-planar imaging (rs-EPI) could significantly reduce magnetic susceptibility artifacts in head and neck regions. In this study, the images were qualitatively evaluated among three types of rs-EPI: with and without readout partial Fourier (RPF), and with simultaneous multi-slice (SMS) technique. The SNRs and CNRs were compared with the additional use of special surface coils (SC). There was no significant differences in the image quality, SNRs, or CNRs among three rs-EPI acquisition methods of all the 31 volunteers and 9 hypopharyngeal carcinoma patients. Markedly, the special surface coils offered better image quality for the evaluation of lower neck lesions.