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Abstract #1134

In vivo Simultaneous Measurement of δf, T1, T2, and T2* by Magnetic Resonance Fingerprinting with Quadratic RF Phase

Charlie Yi Wang1, Simone Coppo2, Bhairav Bipin Mehta2, Nicole Seiberlich1,2, Xin Yu1,2, and Mark Alan Griswold1,2

1Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States, 2Radiology, Case Western Reserve University, Cleveland, OH, United States

We propose a novel Magnetic Resonance Fingerprinting pulse sequence with quadratic RF excitation phase (qRF-MRF) for the purpose of simultaneous measurement of T2* in addition to previously established spin parameters δf, T1, and T2. The original bSSFP based MRF pulse sequence1 was modified to incorporate excitation segments with quadratic RF phase to sensitize signal evolutions to T2*. Measurements using qRF-MRF were performed in both phantom and in vivo. Maps from qRF-MRF were validated against bSSFP based MRF and Multi-GRE.

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