Abstract #1223

4D Flow assessment of arterial pulsation in the patients with internal carotid artery stenotic disease

Takahiro Ando¹, Tetsuro Sekine¹, Yasuo Murai², Ryo Takagi³, Yasuo Amano³, Erika Orita¹, Kotomi Iwata¹, Makoto Obara⁴, Yoshio Matsumura¹, and Shin-Ichiro Kumita¹

¹Radiology, Nippon Medical School, Tokyo, Japan, ²Neurosurgery, Nippon Medical School, Tokyo, Japan, ³Radiology, Nihon University School of Medicine, Tokyo, Japan, ⁴Philips Electronics Japan, Tokyo, Japan

We performed 4D Flow MRI assessment of arterial pulsation in internal carotid artery stenotic disease (ICS) patients comparing to SPECT with acetazolamide challenge. Twelve patients with unilateral ICS were recruited. The blood flow volumes and the ratio of ΔF (rΔF) was calculated. In the affected-side MCA territory, the ratio of rest cerebral blood flow control (RCBF_MCA) and cerebral vascular reserve (CVR_MCA) were calculated from SPECT dataset. rΔF was significantly lower in the low CVR group than high group (P=0.008). The 6-min-standard 4D Flow MRI assessment of arterial pulsation in ICS patients can identify misery perfusion.

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