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Abstract #1254

MR-Based Respiratory and Cardiac Motion Corrected PET/MR

Philip Robson1, MariaGiovanna Trivieri2, Nicolas Karakatsanis1, Ronan Abgral3, Marc Dweck4, Jason Kovacic2, and Zahi Fayad1

1Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States, 2Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States, 3Department of Nuclear Medicine, European University of Brittany, Brest, France, 4British Heart Foundation Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, United Kingdom

A major advantage of hybrid PET/MR systems is the radiation-free high spatial and temporal resolution of MR imaging that can be used to estimate cardio-respiratory motion present during PET data acquisition. This information can be incorporated into reconstruction algorithms to correct for motion in the PET data to reduce blurring and increase target-to-background ratios (TBR) of PET hotspots. This may be of particular importance in cardiac imaging where the heart is in constant motion. In this work, we demonstrate a method for cardio-respiratory motion correction and evaluate the effect on TBR in the myocardium in a cohort of patients.

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