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Abstract #1256

Simultaneous PET and MRSI of Prostate Cancer

Kirsten Margrete Seln├Žs1,2, Morteza Esmaeili1, Nassim Tayari3, Tom Scheenen3, Mattijs Elschot1, Arend Heerschap3, and Tone Frost Bathen1

1Department of Circulation and Medical Imaing, NTNU - Norwegian University of Science and Technology, Trondheim, Norway, 2St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway, 3Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, Netherlands

Both positron emission tomography (PET) and magnetic resonance spectroscopic imaging (MRSI) can give important information about cancer metabolism. With an integrated PET/MR scanner, MRSI and PET images can be acquired simultaneously. The aim of this study was to examine possible correlations between 18F-Fluciclovine PET and MRSI measurements and evaluate their diagnostic performance in prostate cancer. The results showed a significant moderate correlation between both SUVmean and SUVmax and the CCS/C ratio. A combination of the imaging outcomes derived from the integrated PET-MRSI modalities improved the localization accuracy of prostate cancer lesions.

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