Abstract #1266

The presence of brown adipose tissue is associated with thyroid function in subjects with low and normal BMI

Daniela Franz¹, Dominik Weidlich¹, Jan Syväri¹, Maximilian N. Diefenbach¹, Christina Holzapfel², Theresa Drabsch², Thomas Baum³, Holger Eggers⁴, Ernst J. Rummeny¹, Hans Hauner², and Dimitrios C. Karampinos¹

¹Department of Diagnostic and Interventional Radiology, Technical University of Munich, Munich, Germany, ²Else Kröner Fresenius Center for Nutritional Medicine, Technical University of Munich, Munich, Germany, ³Department of Diagnostic and Interventional Neuroradiology, Technical University of Munich, Munich, Germany, ⁴Philips Research Laboratory, Hamburg, Germany

Brown adipose tissue (BAT) is important for energy and glucose metabolism in humans. Thyroid hormones regulate BAT development and function. Proton density fat fraction (PDFF) mapping based on a multi-echo gradient echo acquisition enables spatially-resolved fat quantification and can be indicative of the presence of BAT in adults. This study investigates the relationship between supraclavicular PDFF as surrogate marker for BAT, and serum levels of free thyroxine and free triiodothyronine with body mass index (BMI) as grouping variable.

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