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Abstract #1336

Time-domain EPR imaging with slice selection

Ayano Enomoto1, Ken-ichiro Matsumoto2, Shun Kishimoto1, Shingo Matsumoto3, Murali C Krishna1, and Nallathamby Devasahayam1

1National Cancer Institute, National Institutes of Health, Bethesda, MD, United States, 2Department of Basic Medical Sciences for Radiation Damages, National Institute of Radiological Sciences, Chiba, Japan, 3Graduate school of Information Sicence and technology, Hokkaido University, Sapporo, Japan

The slice selection imaging has advantages of reducing imaging time and obtaining optimum dynamic range in image for EPR imaging as well as for MRI. However, the slice selection using a selective pulse, which is used in MRI, is difficult to implement in EPR imaging because of ultra-fast relaxation time compared to gradient settling time. Therefore, we used a modulated gradient field to achieve slice selection in pulsed EPR imaging in this study. We demonstrated the slice selection imaging with tubes and a living mouse to show the effect of slice selection in pulsed EPR imaging.

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