Mapping of quantitative MRI relaxation values is promising for improving the assessment of MSK disease. Magnetic Resonance Fingerprinting (MRF) is a new method that enables fast quantitative MRI by exploiting the transient signals caused by the variation of pseudorandom sequence parameters.
This proof-of-concept work demonstrates the utility of MR Fingerprinting in the knee. Seven participants, four of which had Kellgren-Lawrence (KL) grade 2 or 3, were imaged eighty minutes after gadolinium injection with MRF on a 3.0T MRI. The mean T1 relaxation times were shorter in cartilage by 5-20% in KL=2,3 subjects when compared to normal subjects.