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Abstract #1439

Towards Whole-Skeleton Fat Fraction Mapping: The Impact of Parallel Imaging

Vruti Dattani1, Tim Bray2, Alan Bainbridge3, and Margaret A Hall-Craggs2

1Royal Free Hospital, London, United Kingdom, 2Centre for Medical Imaging, University College London, London, United Kingdom, 3Department of Medical Physics, University College London Hospitals, London, United Kingdom

Whole body MRI (WB-MRI) is increasingly used to image the skeleton in haematological diseases such as multiple myeloma (MM) and inflammatory disorders such as spondyloarthritis. WB-MRI can be used to acquire fat fraction (FF) maps, which can assess disease severity and treatment response. However, patients with bone pain find it difficult to lie in the scanner for long periods, necessitating the use of parallel imaging to accelerate the acquisition. The aim of this study was to determine the extent to which parallel imaging causes noise artifacts and fat-water swaps in FF maps, and to assess their impact on FF measurements.

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