Purpose: To evaluation quantitative T2 mapping in exploring the effects of prior Gd exposure. Methods: Dual-echo MRI was performed in three groups of subjects; 1) without prior Gd exposure history, 2) only with prior exposure to MultiHance®, and 3) only with prior exposure to Magnevist®. T2 relaxation times were measured in pons, dentate nuclei, globus pallidi and thalami. Results: T2 relaxation time decrease was observed for both contrast agents in dentate nuclei and globus pallidi. Conclusion: Quantitative T2 mapping is a valuable tool in the investigation of Gd deposition in the brain.