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Abstract #1519

Assessment of Approximated Analytical B1+ Correction Method for prostate DCE-MRI with Multiple Noise Levels and in 3.0 T Systems

Xinran Zhong1,2, Thomas Martin1,2, Steve Raman1, Holden H Wu1,2, Krishna Nayak3, and Kyunghyun Sung1,2

1Department of Radiological Sciences, University of California, Los Angeles, Los Angeles, CA, United States, 2Physics and Biology in Medicine IDP, University of California, Los Angeles, Los Angeles, CA, United States, 3Ming Hsieh Department of Electrical Engineering, University of Southern California, Los Angeles, CA, United States

B1+ correction is essential for quantitative prostate DCE-MRI. A simplified approximated analytical B1+ correction method was proposed previously, and we assess this method on a digital reference object (DRO) with various SNR levels and on 110 in-vivo cases from two 3.0 T systems. We find that the approximated analytical B1+ correction method achieves comparable performance to conventional correction method with substantially reduced computation. The approximated analytical correction method is simple and practical for application in the clinic.

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