Abstract #1590

IVIM D and f - Optimal estimation technique and their potential for tissue differentiation

Oscar Jalnefjord^1,2, Mats Andersson³, Mikael Montelius¹, Anna-Karin Elf⁴, Viktor Johanson⁴, Johanna Svensson⁵, Göran Starck^1,2, and Maria Ljungberg^1,2

¹Department of Radiation Physics, University of Gothenburg, Gothenburg, Sweden, ²Department of Medical Physics and Biomedical Engineering, Sahlgrenska University Hospital, Gothenburg, Sweden, ³Department of Radiology, University of Gothenburg, Gothenburg, Sweden, ⁴Department of Surgery, University of Gothenburg, Gothenburg, Sweden, ⁵Department of Oncology, University of Gothenburg, Gothenburg, Sweden

IVIM parameter estimation restricted to D and f (avoiding D*) has gained increased popularity. In this study we show that the commonly used segmented fitting approach is preferable. We also show that differentiation between tumor and healthy liver tissue is substantially enhanced by the combined use of D and f.

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