Inner field-of-view EPI is widely used for diffusion-weighted acquisitions of the human spinal cord. However, due to the high in-plane resolution required acquisition times to achieve a reasonable signal-to-noise ratio are usually rather long. In this study, inner-field-of-view EPI based on 2D-selectove RF excitations is accelerated with multiband excitations. Two different approaches are considered that differ with respect to the orientation of the 2DRF trajectory and whether side excitations must be suppressed or can be used to cover the bands excited and acquired simultaneously. Results obtained in the human brains stem and cervical spinal cord in vivo are presented.