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Abstract #1644

Removal or correction of volumes affected by bulk motion: impact on DTI and NODDI metrics

Kerstin Pannek1, John Welsh2, Jurgen Fripp1, Joanne George3, Paul Colditz3, Roslyn Boyd3, and Stephen Rose1

1CSIRO, Brisbane, Australia, 2University of Newcastle, Newcastle, Australia, 3The University of Queensland, Brisbane, Australia

In difficult patient populations, the interleaved acquisition of diffusion weighted volumes often leads to images that are not self-consistent due to movement. Here, we investigated the effect of removing or correcting volumes with movement artefacts on the DTI measures FA and MD, as well as on NODDI measures. While removal of affected volumes is typically used, we found that a simple correction strategy leads to markedly lower bias and variability in all diffusion measures. Data that may need to be rejected entirely if volume removal is used, may be salvaged if correction is used.

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