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Abstract #1646

Intravoxel Incoherent Motion (IVIM) Fingerprinting

Qiuting Wen1, Li Feng2, Kun Zhou3, and Yu-Chien Wu1

1Center for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana University, School of Medicine, Indianapolis, IN, United States, 2Center for Advanced Imaging Innovation and Research (CAI2R), New York University, School of Medicine, New York, NY, United States, 3Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China

Intravoxel incoherent motion (IVIM) imaging employs a bi-exponential diffusion model to estimate capillary contributions to the diffusion-weighted signal. Major challenges of IVIM are long acquisition time, long processing time, and image distortion associated with EPI acquisition. In this work, we proposed a novel framework for rapid and distortion-free IVIM imaging called IVIM-Fingerprinting. It employs a single-shot acquisition scheme and an advanced image reconstruction scheme in combination with the recently proposed concept of MR Fingerprinting. Its performance was demonstrated both for simulation and for in-vivo studies.

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