Abstract #1676

Diffusion Weighted Imaging with uniform fat suppression using a Modified Dixon based Single Shot Turbo Spin Echo

Xinzeng Wang¹, Holger Eggers², Marco C. Pinho^1,3, Ivan Pedrosa^1,3,4, Robert E. Lenkinski^1,3, and Ananth J. Madhuranthakam^1,3

¹Radiology, UT Southwestern Medical Center, Dallas, TX, United States, ²Philips Research, Hamburg, Germany, ³Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States, ⁴Kidney Cancer Program, Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX, United States

Diffusion weighted imaging using single-shot turbo spin echo (DW-SShTSE) with Dixon showed uniform fat suppression without geometric distortions, compared to DW-EPI and DW-SShTSE with spectrally selective fat suppression (SPIR). However, the phase insensitive preparation used in DW-SShTSE reduces the SNR by half, impeding the robustness of Dixon reconstruction. In this work, we developed a hybrid DW-SShTSE, where the b=0 s/mm² image was acquired without the phase insensitive preparation for improved SNR. This combined with modified acquisition order improved the robustness of fat/water separation and generated diffusion-weighted images of the cervical spine with improved spatial resolution.

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