In this work, highly efficient 300 W digitally controlled supply-modulated Class-E amplifiers for two-channel RF transmit array are presented. Load pull analysis is performed for load optimization purposes. Coupling between the transmit coils is measured to be 8% when 12 cm diameter coils are placed with a distance of 7 cm. The performance of amplifiers while working simultaneously at same frequency and at different frequencies is evaluated. MR experiments are conducted and it is observed that MR images show no artifact in the presence of amplifier near transmit coil inside the scanner.