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Abstract #1820

Grey abnormalities associate with suicide related behaviour in first episode non-affective psychosis patients

Manuel Canal-Rivero1,2, Rosa Ayesa-Arriola2,3, Esther Setien-Suero2,3, Manuel Delgado-Alvarado1, Benedicto Crespo-Facorro2,3, and Diana Tordesillas-Gutierrez1,2

1Neuroimaging Unit, Technological Facilities, IDIVAL, Santander, Spain, 2CIBERSAM, Santander, Spain, 3University Hospital Marqués de Valdecilla, School of Medicine, University of Cantabria, IDIVAL, Santander, Spain

Little is known about brain abnormalities associated with suicide-related behaviours in first episode psychosis patients and controversial results have been reported. The main aim of the present study was to examine brain abnormalities related with suicidal behaviours in a large sample of first episode psychosis (FEP) patients. In particular, we found reduction grey matter volume in frontal area, middle temporal gyrus as well as posterior cingulate gyrus and precuneus. These areas appear to be associated with some of the greatest features related to suicidal behaviour such as impulsivity, emotional processing information, responses to pain and aggressiveness.

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