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Abstract #1868

Magnetic resonance angiography and venography was not useful for correcting underestimated susceptibility measurements of sub-voxel objects on quantitative susceptibility maps

Natalie M Wiseman1, Sagar Buch2, Yongsheng Chen3, E Mark Haacke3,4, and Zhifeng Kou3,4

1Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI, United States, 2Center for Functional and Metabolic Mapping, Robarts' Research Institute, Western University, London, ON, Canada, 3Department of Radiology, Wayne State University, Detroit, MI, United States, 4Department of Biomedical Engineering, Wayne State University, Detroit, MI, United States

We investigated two magnetic resonance angiography and venography (MRAV) methods for use in correcting quantitative susceptibility mapping (QSM) estimates in sub-voxel veins. An MRAV generated from an interleaved rephased/dephased gradient echo sequence (without contrast agent) suffered from low SNR in veins, whereas the contrast-enhanced T1-MRAV caused the vessels to appear larger than those in the pre-contrast images. Neither method offered a reliable correction of partial-volumed susceptibility measurements.

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