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Abstract #1905

Language reorganization in pre-and post-operative drug refractory extra temporal lobe epilepsy patients: An fMRI based study

Kapil Chaudhary1, Senthil Kumaran2, Sarat P Chandra3, Ashima Nehra Wadhawan4, and Manjari Tripathi1

1Department of Neurology, All India Institute of Medical Sciences, New Delhi, India, 2Department of NMR and MRI Facility, All India Institute of Medical Sciences, New Delhi, India, 3Department of Neuro-Surgery, All India Institute of Medical Sciences, New Delhi, India, 4Department of Clinical Neuropsychology, All India Institute of Medical Sciences, New Delhi, India

Drug refractory epilepsy (DRE) patients have atypical language lateralization with ipsilateral and contra lateral hemispheric lesions and pathological abnormalities. Such kind of patients may have different language recovery after surgery. In this study, we have used a standardized Hindi-language paradigm using semantic, syntactic, judgement and comprehension components for testing in the North-Indian population. We observed greater improvement in language skills in ETLE-patients with correspondingly greater recruitment of the bilateral hemisphere.

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