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Abstract #1988

Diffusivity and the neurocognitive domains of premorbid intelligence and visuospatial memory in Pediatric Multiple Sclerosis

Sindhuja T. Govindarajan1, M. Andrea Parra2, Tao Wang1, Kenneth Wengler1, Chuan Huang2, Xiang He2, Leigh Charvet3, Lauren Krupp3, and Tim Q Duong2

1Stony Brook University, Stony Brook, NY, United States, 2Stony Brook University School of Medicine, Stony Brook, NY, United States, 3New York University Langone Medical Center, New York, NY, United States

DTI has been commonly used to study multiple sclerosis (MS) patients1-3 and many studies have correlate DTI parameters with neurocognitive functions. However, only a handful of studies4, 5 have characterized such relationships in pediatric MS patients. The goal of this study was to investigate DTI characteristics in pediatric onset MS patients and to correlate them with neurocognitive functions (intelligence and visuospatial memory).

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