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Abstract #2072

Differentiation and Quantification of White Matter Injury in Post-Hemorrhagic Hydrocephalus

Albert M. Isaacs1, Harri Merisaari2, Tsen-Hsuan Abby Lin2, James (Pat) James McAllister3, David D Limbrick3, and Sheng-Kwei (Victor) Song2

1Neuroscience, Washington University School of Medicine, St. Louis, MO, United States, 2Radiology, Washington University School of Medicine, St. Louis, MO, United States, 3Neurosurgery, Washington University School of Medicine, St. Louis, MO, United States

This study is the first of its kind, and uses diffusion basis spectrum imaging (DBSI) to quantify, as well as differentiate the complex pathologies that underlies the white matter injury in post-hemorrhagic hydrocephalus (PHH) in neonates, using a ferret model of PHH.

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