Comparison of optimized single-PLD, sequential multi-PLD and time-encoded PCASL for cerebral blood flow measurements
Joseph G. Woods1, Michael A. Chappell2, and Thomas W. Okell1
1Wellcome Centre for Integrative Neuroimaging, FMRIB, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, United Kingdom, 2Institute of Biomedical Engineering, University of Oxford, Oxford, United Kingdom
In this work, we use an objective approach to optimize sequential and time-encoded multi-PLD protocols, and compare them to the recommended single-PLD protocol using simulations, with the aim of determining which method is capable of producing the most accurate CBF estimates across a range of ATTs.
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