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Abstract #2193

Fast Zoomed QSM of the Human Midbrain at 7T

Kyungmin Nam1,2,3,4, Namgyun Lee1, Anouk Marsman1, Vincent Oltman Boer1, Chulhyun Lee3,4, and Esben Thade Petersen1,2

1Danish Research Center for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark, 2Center for Magnetic Resonance, Department of Electrical Engineering, Technical University of Denmark, Lyngby, Denmark, 3Bio-Imaging Research Team, Korea Basic Science Institute, Cheongju, Republic of Korea, 4Bio-Analysis Science, University of Science and Technology, Daejeon, Republic of Korea

In this work, zoomed quantitative susceptibility mapping (QSM) is proposed as an alternative way of accelerating high resolution QSM data acquisition at 7T. Inner volume excitation is realized with 2D spatially selective excitation, targeting the midbrain, which is the primary region of investigation for Parkinson’s disease. The consequence of reducing the excited region on the reconstructed susceptibility maps was investigated via simulations, where the diameter of a brain mask was gradually decreased in the QSM processing pipeline. The susceptibility maps of a healthy volunteer at 7T acquired with inner volume excitation are compared to those derived from a whole brain.

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