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Abstract #2219

Reproducibility of Quantitative Susceptibility Mapping and R2* Mapping of the Human Brain at 7T: a Multi-Centre Pilot Study

Catarina Rua1, William T Clarke2, Ian D Driver3, Olivier Mougin4, Stuart Clare2, Susan Francis4, Keith Muir5, Richard Wise3, Guy Williams1, Richard Bowtell4, and Adrian Carpenter1

1Department of Clinical Neurosciences, University of Cambridge, Wolfson Brain Imaging Centre, Cambridge, United Kingdom, 2University of Oxford, Welcome Centre for Integrative Neuroimaging (FMRIB), Oxford, United Kingdom, 3School of Psychology, Cardiff University, Cardiff University Brain Research Imaging Centre, Cardiff, United Kingdom, 4University of Nottingham, Sir Peter Mansfield Imaging Centre, Nottingham, United Kingdom, 5University of Glasgow, Institute of Neuroscience & Psychology, Glasgow, United Kingdom

To perform cost-effective research with high-field imaging by increasing the size of the patient pool in investigations of brain diseases, it is important to guarantee cross-site reproducibility and consistency of the QSM and R2* results. This study is part of a pilot “travelling-heads” experiment from the UK7T network, in which we aim to develop harmonized approaches for T2*-weighted imaging in order to provide a framework for future multi-centre clinical studies at 7T.

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