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Abstract #2354

Changes in functional connectivity in the ventral attention system

Louis Gudmundsson 1,2, Jakub Vohryzek1, Eleonora Fornari3, Stephanie Clarke2, Patric Hagmann1, and Sonia Crottaz-Herbette2

1Department of Radiology, Centre Hospitalier Universitaire Vaudois (CHUV), and University of Lausanne, 1011 Lausanne, Switzerland, Unil, Lausanne, Switzerland, 2Neuropsychology and Neurorehabilitation Service, Centre Hospitalier Universitaire Vaudois (CHUV), and University of Lausanne, 1011 Lausanne, Switzerland, Unil, Lausanne, Switzerland, 3CIBM (Centre d'Imagerie Biom├ędicale), Dept. of Radiology, Centre Hospitalier Universitaire Vaudois (CHUV), and University of Lausanne, 1011 Lausanne, Switzerland, Unil, Lausanne, Switzerland

Prismatic adaptation (PA), a therapy for neglect after a stroke, showed conflicting results in the literature. The variability of brain lesions leading to neglect and their relation to structures affected by PA could explain those results. MRI studies found focal brain activations after PA. We aim to understand if there is an effect on functional networks after PA. To do so, we analyzed the resting state fMRI connectivity of healthy subjects before and after PA. We found that the ventral attention system (VAS) was less connected after PA, this provides new insights to select patients for this therapy.

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