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Abstract #2373

Neural mechanism of reward circuit in exercise addiction : an fMRI study

Kyung Eun Jang1, Yang-Tae Kim2, Jingu Kim3, Hyunsil Cha1, Heajung Choi1, Eunji Kim1, Moojin Yang1, Jiung Yang1, Huijin Song4, Moon Jung Hwang5, and Yongmin Chang1,6

1Medical & Biological Engineering, Kyungpook National University, Daegu, Republic of Korea, 2Psychiatry, School of Medicine, Keimyung University, Daegu, Republic of Korea, 3Physical Education, Kyungpook National University, Daegu, Republic of Korea, 4Biomedical Engineering Research, Kyungpook National University, Daegu, Republic of Korea, 5GE Health Korea, Seoul, Republic of Korea, 6Radiology and Molecular Medicine, College of Medicine, Kyungpook National University, Daegu, Republic of Korea

We investigate neural activation of physical exercise related pictures in exercise addiction. Our results demonstrate that exercise addiction group showed lower activation in ventral striatum than the moderate exercise group, indicating that dopamine release of the ventral striatum in exercise addiction group may reduce because of withdrawal symptoms and negative prediction error. Moreover, we found that exercise addiction group showed less activation in the posterior orbitofrontal cortex than the other groups, suggesting that exercise addiction group may not deliberate fitness equipment and body shape of exerciser as reward value.

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