Dynamic oxygen–enhanced MRI (dOE-MRI) techniques have previously been apply to study the rate and level of O2 enhancement in the lung. Lung MRI investigations are mostly conducted at 1.5T, because signal loss due to stronger susceptibility artefacts in lung tissue is expected at higher field strength. In this work, we demonstrate the feasibility of dOE-MRI at 3T on healthy volunteers. The observed signal enhancement is comparable between 1.5T and 3T, but translates in a lower relative T1 change due to higher baseline T1 at 3T. Fitting performance of O2 wash-in curve may be reduced by the lower SNR at 3T.