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Abstract #2495

R1rho dispersion in human kidney

Ping Wang1 and John C. Gore1

1Radiology and Radiological Sciences, Vanderbilt University Institute of Imaging Science, Nashville, TN, United States

R (=1/T) imaging has been applied in many human organs to characterize tissue biochemical changes. However, R imaging in human kidney has been rarely reported partly due to the challenges associated with field inhomogeneities and respiratory motion. We developed an R imaging protocol for human kidney which used adiabatic half passage pulse and volume shimming to overcome field inhomogeneities. In addition, R dispersion was evaluated via a simple method with a fixed locking time but different locking frequencies. The volunteer scans exhibited characterized R maps in kidney, also there was greater R dispersion between locking frequencies of 100Hz and 300Hz.

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