Abstract #2498

Differentiating supraclavicular from gluteal adipose tissue based on simultaneous PDFF and T2* mapping using a twenty-echo gradient echo acquisition

Daniela Franz¹, Maximilian N. Diefenbach¹, Jan Syväri¹, Dominik Weidlich¹, Ernst J. Rummeny¹, Hans Hauner², Stefan Ruschke¹, and Dimitrios C. Karampinos¹

¹Ismaninger Str. 22, Department of Diagnostic and Interventional Radiology, Technical University of Munich, Munich, Germany, ²Else Kröner Fresenius Center for Nutritional Medicine, Technical University of Munich, Munich, Germany

PDFF and T2* have been previously proposed as two important parameters in quantitative MRI of adipose tissue. This study investigates the difference between gluteal and supraclavicular adipose tissue T2* and the relationship between adipose tissue T2* and PDFF using a twenty-echo multi-echo gradient echo acquisition. A highly significant difference between the PDFF in different fat regions was detected in water-fat separation results when using either the first 6 echoes or the full 20 echoes. However, T2* values were only significantly different between fat regions, when using the full 20 echoes and not when using the first 6 echoes. PDFF also correlated with T2* when using the full 20 echoes.

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