T2W imaging is an important sequence in the PIRADSv2 guideline for scoring prostatic lesions. The apparent contrast between malignant and non-malignant tissues on T2W images depends on the time of echo (TE). In this study we have investigated the effect of TE on the contrast-to-noise ratio (CNR) between malignant and non-malignant tissues. We have acquired and analyzed T2W data from 12 patients. Our results show that CNR increases abruptly for TEs between 25 and 175ms. After CNR reaches its maximum at 175ms it gradually decreases. Our findings may be used toward improvement of T2W protocols for diagnosis of prostatic carcinoma.