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Abstract #2560

Performance of PIRADSv2 ≥3 and ≥4 scores as cut-offs for the detection of prostate cancer

Chandan J Das1, Vivek Lanka1, Sanjay Sharma1, Rishi Nayyar2, and Virendra Kumar3

1Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India, 2Department of Urology, All India Institute of Medical Sciences, New Delhi, India, 3Department of NMR, All India Institute of Medical Sciences, New Delhi, India

We report a prospective evaluation of prostate imaging reporting, archiving and data system version 2 (PIRADSv2) for multiparametric MRI (mpMRI) taking histopathology of radical prostatectomy specimens as reference standard. PIRADSv2 for mpMRI is easy to apply for detection of cancer of prostate (CaP) at optimal cut-offs of ≥3 for cancer as a whole and ≥4 for intermediate and high grade cancers. It is an accurate system to diagnose clinically significant disease. 26 patients having a biopsy-proven CaP, were investigated at 3.0T using mpMRI, followed by radical prostatectomy within 1 month. Gleason grade group from radical prostatectomy specimens and ROC curve analysis was used to determine the accuracy for cut-offs for scores of PIRADSv2.

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Abstract